Research Program

Research Programs

Faculty and staff from Biomanufacturing Training and Education Center (BTEC), departments within the College of Engineering, and the College of Textiles are collaborating with faculty from the Technical University of Denmark (DTU) on projects that range from cell factory engineering to upstream bioreactor design and optimization and to downstream capture and purification operations. Projects, principal investigators (PIs) and co–PIs are shown below.

Projects

Perfusion system for high yield production of complex proteins and glycoproteins

Next-gen brewing: Therapeutic activity and manufacturability of probiotic yeast

Novel biosensors for product quality attributes and contaminant detection

Yeast cell factory design and high-throughput screening for therapeutic protein production

Peptide-based adsorbents for affinity-based capture of next generation therapeutics

Nonwoven membranes for high-throughput chromatographic separations

Single-use technology for the flow-through polishing of protein therapeutics

ISPR: Evaluation of in-situ product removal for therapeutic proteins

Virtual pilot plant – Towards a digital process twin for efficient learning and experimental planning

Other NC State faculty and staff contributing to these
projects include:

From DTU, also contributing to these research projects are:

The Crook Lab Space
Crook Lab

Key:

BME: Biomedical Engineering
CBE: Chemical and Biomolecular Engineering, College of Engineering
ECE: Electrical and Computer Engineering, College of Engineering
COT: College of Textiles